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DE111®: Promotes Healthy Regularity

Category: Educational Articles

Nobody really likes extremes – such as extremely hot and humid days in the summer to bitter, Arctic cold in the winter, or a too-sweet or too salty food. And, even occasional constipation and its opposite, diarrhea, is no picnic, either.

The “occasional irregularity” when it does occur, swiftly causes discomfort, sometimes even angst, depending upon the person’s situation (working outdoors, for example, and not being near a bathroom when the “feeling” hits.)

The gastrointestinal system is often quite persnickety. It is somewhat akin to a highway – sometimes traffic snarls and clogs, and sometimes when it’s empty, there’s always that show-off speeder who zooms by.

When one deals with both on a more frequent basis, this is the hallmark of irritable bowel syndrome (IBS), which is a medical diagnosis. In absence of IBS, people can become constipated due to medications (antidepressants, pain relievers, iron supplements), lack of sufficient fiber in the diet and hormone fluctuations. Occasional diarrhea not caused by pathogenic bacteria or virus is caused by stress and anxiety (which alters hormone release affecting the GI tract), some prescriptions, and some foods the individual may be sensitive to.

Preventing the occasional irregularity is desirable for multiple millions of healthy Americans who just don’t have time for “bathroom issues.” And, we have a new study, published in the Journal of Probiotics & Health, that shows our DE111® is such an effective solution.

The study included 50 individuals who supplemented with a placebo or one capsule of Bacillus subtilis DE111® supplying 1 billion CFU for 105 days. The participants supplied stool samples that were scored based on the Bristol Stool Chart index, kept a detailed food diary and filled out questionnaires.

The DE111 supplemented group experienced a modulation of bouts of constipation and diarrhea, showing a healthier bowel index – but no change in alternating constipation and diarrhea for the placebo group. Specifically, the proportion of normal stools increased from 37% to 43% in the DE111 group, while the proportion of normal stools remained the same in the placebo group. Interestingly, men taking DE111 had dramatic results – normal stools in this group inclined from 56% to 80%. The supplement also delivered similar impact on those participants 30 and older.

For consumers mindfully living a healthy lifestyle, the occasional extreme of constipation and diarrhea can be less than, well, occasional.

About DE111®
DE111 is a genome-sequenced and clinically tested strain of Bacillus subtilis, a probiotic spore that supports digestive and immune health. The genome sequencing confirmed the strain contained no plasmids, antibiotic resistant or deleterious genes; the human clinical studies showed the strain’s ability to control microbial populations, aid in digestion and maintain general health. DE111 is able to form spores that protect the microbes from harsh conditions until they enter an environment ripe for germination, such as the GI tract. Because of this spore-forming ability, DE111 remains viable under a wide temperature and pH range, making it ideal for use in supplements as well as food and beverages.

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About The Expert
John Davidson
Director of Education and Innovation, Deerland Enzymes & Probiotics

John Davidson has been formulating enzyme based dietary supplements for more than 30 years, with a particular focus in human digestion. Davidson’s wide range of experience encompasses nearly all aspects of supplement manufacturing; including QC/QA, blending, encapsulation, tableting, research & development, product development and technical services. In his current role as the Director of Education and Innovation for Deerland Probiotics & Enzymes, Davidson is responsible for both new product innovation, collaborating with R&D and Sales to bring new products to market.

John Davidson

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